Adverse events associated with glucocorticoid-related intestinal microbiota disturbances in hypertensive patients during pregnancy: prospective controlled study protocol

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300078466

Enrollment

Unknown

Registered

2023-12-08

Start date

2024-01-01

Completion date

Unknown

Last updated

2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive disorder complicating pregnancy

Interventions

Control group:NA

gestational hypertension did not use glucocorticoids during pregnancy:NA

gestational hypertension was used glucocorticoids during pregnancy:NA

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age > 18 years, age at delivery <35 years, single pregnancy, gestational age 12-14 weeks ultrasound indicates normal intrauterine pregnancy.

Exclusion criteria

Exclusion criteria: Diagnosed psychiatric disorders, diagnosed intestinal disorders, illicit drug use, antibiotic use, prebiotic or probiotic supplementation, pregnancy beyond 12 weeks of gestation at time of recruitment, preconception diabetes, hypertension or other serious illness, other comorbiditions such as gestational diabetes, multiple pregnancies, previous bariatric surgery, alcohol or drug abuse.

Design outcomes

Primary

Measure	Time frame
Intestinal flora;pregnancy outcome;	—

Countries

China

Contacts

Public ContactMan Guo

the Second Affiliated Hospital of Harbin Medical

51864118@qq.com+86 136 5454 4297

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026