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Risk Prediction of New Vertebral Fractures After PVP for Patients with Vertebral Compression Fractures Based on Bone Metabolic Markers: Development of a Prediction Model

Risk Prediction of New Vertebral Fractures After PVP for Patients with Vertebral Compression Fractures Based on Bone Metabolic Markers: Development of a Prediction Model

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078451
Enrollment
Unknown
Registered
2023-12-08
Start date
2023-04-20
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporotic vertebral compression fractures

Interventions

Grouping based on the occurrence of recurrent vertebral fractures:None

Sponsors

Shaoguan First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1: Two-photon bone mineral density examination T value =-2.5 2: MRI examination indicated fresh vertebral fracture 3: The patient consented to the first PVP surgery 4: The disease is non-secondary osteoporosis. No diseases that affect bone metabolism, such as hyperparathyroidism 5: Patients volunteered to participate in this study and signed informed consent

Exclusion criteria

Exclusion criteria: 1: Osteoporosis caused by hyperparathyroidism and other diseases 2: History of taking drugs that affect bone metabolism 3: Previous history of spinal surgery 4: Cancer patients, patients with mental illness and other special groups 5: People with poor adherence who cannot complete the study 6: Other conditions that researchers deem inappropriate for inclusion in the study

Design outcomes

Primary

MeasureTime frame
Bone Metabolic Markers;

Secondary

MeasureTime frame
Refracture after PVP;Bone mineral density;Visual Analogue Score;The Oswestry Disability Index;ROC curve, area under the curve (AUC value);Sensitivity, specificity, accuracy;

Countries

China

Contacts

Public ContactQiang Wu

Shaoguan First People's Hospital

sgwuqiang@sina.com+86 135 0986 6960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026