generalized anxiety disorder with insomnia
Conditions
Interventions
treatment group:Tongren niuhuang qingxin pills
control group:Lorazepam Tablets
Sponsors
The Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) The age ranged from 18 to 65 years. (2) Patients with generalized anxiety who conformed to the criteria for a clinical study. (3) Meet the Traditional Chinese Medicine (TCM) syndromes of Phlegm and heat disturbing the heart. (4) Meet the diagnostic criteria for insomnia. (5) Vital signs are stable, clear mind and expressive ability. (6) Sign informed consent.
Exclusion criteria
Exclusion criteria: (1)Physical illness secondary to generalized anxiety disorder, such as coronary heart disease, cerebrovascular disease, hypertension, diabetes, thyroid disease, etc. (2)Patients with unstable vital signs. (3)Severe aphasia, agnosia and inability to communicate. (4)Anxiety associated with other mental disorders (like depression, obsessive-compulsive disorder, schizophrenia) clinically diagnosed by western medicine. (5)People who suffer from insomnia due to drug abuse or excessive alcohol consumption, coffee, strong tea, and adverse life factors. (6)People with known alcohol or drug dependence. (7)Patients clinically diagnosed with non-anxiety psychosis by western medicine. (8)Other traditional Chinese medicines or therapy for anxiety and insomnia were also used during the study. (9)Not taking medications as prescribed, unable to determine efficacy, and incomplete data affect the efficacy or safety. (10)Those who refused to take medication and had committed suicide. (11)Patients who had received anti-anxiety treatment within 1 week before the test. (12)Severe hepatic and renal insufficiency. (13)Pregnant and lactating women. (14)Patients who met other syndrome criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale;Pittsburgh sleep quality Index;Traditional Chinese Medicine Syndrome Score;Determination of inflammatory cytokines in serum specimens;Determination of neurotransmitter in serum specimens; | — |
Secondary
| Measure | Time frame |
|---|---|
| Short form 36 questionnaire;Stroop color and word test; | — |
Countries
CHINA
Contacts
Public ContactQu Miao
The Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine
Outcome results
None listed