Postoperative sleep disturbance
Conditions
Interventions
Intervention group (k group):Under ultrasound guidance, a total of 5ml of 0.2% ropivacaine with normal saline +0.05mg/kg esketamine was administered with right stele ganglion block + 50mg to 50ml of e
Control group (c group):Normal saline was prepared with esketamine 50mg to 50ml empty needle, and continued intravenous pump at 0.3mg/kg.h at the beginning of the operation, and the use was discontinu
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18 years old = age =65 years old, gender is not limited; 2. 30 kg/m2 = BMI > 18kg/m2; 3. Adult patients undergoing gynecological laparoscopic surgery under general anesthesia; 4. ASA grade I - III; 5. Fully informed and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with BMI > 30kg/m2 and BMI < 18kg/m2; 2. Patients with contraindications and allergies to esketamine, ropivacaine, dexmedetomidine; 3. During pregnancy and lactation; Surgery that may increase intracranial and intraocular pressure (e.g. removal of intracranial hematoma, glaucoma surgery); Uncontrolled hyperthyroidism, apparent ischemic heart disease (unstable angina or myocardial infarction in the last 6 months). 4. Central nervous system disease, inability to communicate with mental illness, abuse of opioids, benzodiazepines; People who have taken sedation and sleeping pills to fall asleep in the past month, have not completed 9 years of compulsory education, and have cognitive disabilities; 5. Severe liver dysfunction (Child-Pugh C grade), severe renal dysfunction (preoperative dialysis), or ASA=IV grade of the American College of Anesthesiologists; 6. Abnormal coagulation function, puncture site infection or hematoma, peripheral nerve injury or lesion, severe respiratory and circulatory disease (New York Heart Function Scale greater than 2 or six minute walk test less than 400 meters).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PSQI; | — |
Secondary
| Measure | Time frame |
|---|---|
| AIS;HADS;VAS;Sleep remedy; | — |
Countries
China
Contacts
Public ContactLihua Peng
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed