Ischemic stroke
Conditions
Interventions
Experimental group:On the basis of basic treatment (reducing intracranial pressure, anti platelet aggregation, controlling blood lipids and blood sugar, correcting water electrolyte disorders, nutriti
control group:On the basis of basic treatment (reducing intracranial pressure, anti platelet aggregation, controlling blood lipids and blood sugar, correcting electrolyte imbalances, nutritional suppo
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 35 to 80 years old, regardless of gender; 2. <48 hours from onset to treatment; The time when symptoms begin is defined as the 'last time they appear normal'; 3. Clinical diagnosis of ischemic stroke (diagnosis follows the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018"); 4. MRS = 1 point before onset, baseline 4 = NIHSS = 24 points; 5. The subject or their trustee agrees and voluntarily signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Age range from 35 to 80 years old, regardless of gender; 2. ULN; Those who have been assessed by researchers as unable to cooperate in completing clinical trials in terms of their psychological, mental or cognitive abilities, language expression abilities, etc; 5. After active antihypertensive treatment, hypertension remains uncontrolled: systolic blood pressure = 220mmHg, or diastolic blood pressure = 120mmHg, with acute bleeding tendencies, including platelet counts below 75.0 × 10 ^ 9/L or other circumstances; Blood glucose22.22mmol/L; 6. Pregnant women, lactating women, or subjects who do not agree to effective contraceptive measures during the trial period; Suspected or with a history of alcohol or drug abuse; 7. Participate in other clinical trials within 3 months prior to screening; 8. According to the judgment of the researcher, it is not suitable to participate in this study or participating in this study may result in greater risk for the subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| NIHSS score; | — |
Countries
China
Contacts
Public ContactWang Chaoxia
Peking University First Hospital
Outcome results
None listed