Peripheral Artery Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients Group: Patients with Critical Limb Ischemia (CLI) are recruited from the outpatient and inpatient departments of Shanxi Bethune Hospital. Inclusion criteria: (1) Meet the diagnostic criteria for CLI; (2) Aged 50-80 years, gender not specified, right-handed; (3) Have not taken any psychoactive drugs in the month prior to enrollment; (4) Willingly participate in this study and sign an informed consent form. 2. Healthy control Group: A healthy control group is recruited concurrently. Inclusion criteria: (1) Select individuals whose gender, age, and educational level match those of the experimental group; (2) Aged 50-80 years, gender not specified, right-handed; (3) Have never received any psychoactive drugs or undergone brain physical therapy.
Exclusion criteria
Exclusion criteria: 1. Patients Group: (1) Pain not caused by CLI in the past month; (2) Suffering from other mental illnesses or organic brain diseases; (3) History of receiving physical therapies like electroconvulsive therapy or transcranial magnetic stimulation; (4) History of drug abuse or addiction; (5) Contraindications for MRI, such as claustrophobia or internal metal implants. 2. Healthy control Group: (1) Past diagnosis of mental disorders; (2) Family history of mental disorders or organic brain diseases; (3) History of pain in the past month; (4) Contraindications for MRI, such as claustrophobia or internal metal implants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI data ; | — |
Secondary
| Measure | Time frame |
|---|---|
| MoCA scale;NRS scale; | — |
Countries
China
Contacts
Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences; Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University