Respiratory Disease
Conditions
Interventions
Experimental group:Respiratory function recovery window appears and airway protection ability is achieved through sequential non-invasive mechanical ventilation after extubation
Control group:After passing the assessment of SBT and airway protection ability, extubate and provide respiratory support as needed.
Sponsors
Dazhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age 18-80 years old; After the occurrence of acute respiratory failure, invasive mechanical ventilation treatment has been carried out for more than 24 hours, and the expected duration of invasive mechanical ventilation is = 2 days.
Exclusion criteria
Exclusion criteria: Severe heart, brain, liver, and kidney failure; Severe malnutrition; advanced tumor; tracheostomy; Inability to wear a nasal mask due to upper airway or facial injury; Unable to cooperate with non-invasive mechanical ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital signs occur when the window for recovery of respiratory function occurs;Laboratory findings when the window for respiratory recovery occurs;The window of recovery of respiratory function occurs when arterial blood gases occur;Sequential non-invasive ventilation of daily arterial blood gases;Weaning time for invasive ventilation;Invasive mechanical ventilation duration;Total mechanical ventilation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs on admission;Laboratory findings on admission;Arterial blood gases on admission;SOFA score;28 days without mechanical ventilation;Successful weaning extubation rate;Stay in the ICU for a long time;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactXiaoyi LIU
Dazhou Central Hospital
Outcome results
None listed