Acute watery diarrhea in children (Damp-heat syndrome)
Conditions
Interventions
Experimental:HC001 granule
Control:Very low dose HC001 granules
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 5 Years
Inclusion criteria
Inclusion criteria: 1 It is consistent with the Western diagnostic standard of acute watery diarrhea in children and the TCM syndrome differentiation standard of damp-heat syndrome 2 Stool characteristics were Bristol-grade 7 or 6 3 The course of diarrhea is less than 72 hours, and the disease is mild or medium 4 Age 1-5 years old (< 6 years old) 5 The informed consent process shall be in accordance with the regulations, and the legal guardian of the tested child will sign the informed consent voluntarily
Exclusion criteria
Exclusion criteria: 1 Acute diarrhea severe, or frequent vomiting unable to ingest diet 2 Watery diarrhoea due to other causes, such as primary lactase deficiency, glucose-galactose malabsorption, chlorinated diarrhoea, primary bile acid malabsorption, etc., or food protein-induced enteropathy, or due to specific pathogenic agents (e.g. cholera) 3 Dysentery diarrhea (naked mucus, pus and blood stool), or stool microscopic examination found pus/white blood cells =5 /HP and/or red blood cells =3 /HP 4 Symptomatic diarrhea, or antibiotic-associated diarrhea, or diarrhea caused by food poisoning 5 Patients with severe primary diseases of heart, liver, kidney, digestive and hematopoietic systems, or severe malnutrition 6 Allergic to the experimental drug and its ingredients 7 The researchers did not consider it suitable for induction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of diarrhea(Total effective rate and Marked effective rate);Onset time of antidiarrhea(hours);Curative effect of TCM syndrome;Continuous time of diarrhea/ time of antidiarrhea(hours); | — |
Countries
China
Contacts
Public ContactZailing Li
Peking University Third Hospital
Outcome results
None listed