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Comparison of the incidence of reflux after H anastomosis and non-intussuscepted anastomosis in Mekown esophagectomy—a multicenter, open-labeled, parallel, randomized controlled study

Comparison of the incidence of reflux after H anastomosis and non-intussuscepted anastomosis in Mekown esophagectomy—a multicenter, open-labeled, parallel, randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078347
Enrollment
Unknown
Registered
2023-12-06
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

H anastomosis group:H anastomosis
Non-intussuscepted anastomosis group:Non-intussuscepted anastomosis Including mechanical end-to-end anastomosis, manual end-to-end anastomosis, and manual layered end-to-end anastomosis

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Age range from 18 to 75 years old, regardless of gender. 2) The preoperative pathological diagnosis under gastroscopy was esophageal squamous cell carcinoma. 3) According to the 2017 edition of the UICC/AJCC staging criteria, the surgical assessment is for a surgical lesion. 4) There are no obvious surgical contraindications for evaluating the main organ function through preoperative auxiliary examinations. 5) Those who plan to undergo Mecknewn esophageal cancer resection surgery. 6) The subjects voluntarily joined this study, signed an informed consent form, had good compliance, and cooperated with follow-up.

Exclusion criteria

Exclusion criteria: 1) Previous history of upper abdominal or chest trauma and surgery; 2) Previously or simultaneously suffering from other malignant tumors.

Design outcomes

Primary

MeasureTime frame
Incidence of gastroesophageal reflux;

Secondary

MeasureTime frame
Quality of life;BMI;Dysphagia;Quality of sleep;DeMeester score;

Countries

China

Contacts

Public ContactHu Yang

West China Hospital, Sichuan University

huyangthoracic@126.com+86 189 8060 6876

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026