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Analysis of the effect of oxycodone preadministration timing on clinical anesthesia in laparoscopic surgery: a prospective, randomized, double-blind experimental study

Analysis of the effect of oxycodone preadministration timing on clinical anesthesia in laparoscopic surgery: a prospective, randomized, double-blind experimental study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078324
Enrollment
Unknown
Registered
2023-12-05
Start date
2023-12-05
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic surgery

Interventions

Group A:Group A was given 0.1mg/kg oxycodone by slow intravenous injection 10 minutes before induction
Group B:group B was given 0.1mg/kg oxycodone by slow intravenous injection 10 minutes before the end of surgery (immediately after suture)

Sponsors

Department of Anesthesiology, Lu 'an Hospital of Traditional Chinese Medicine, Anhui Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: inclusion criteria (1) Informed consent, voluntarily participate in the test, and sign the informed consent; (2) Patients aged between 20 and 65 years old were used as research objects; (3) The patient had no history of opioid abuse; (4) Routine indexes such as liver, kidney and coagulation function were normal before operation; (5) The patient was well-nourished with a BMI of 18.5-28

Exclusion criteria

Exclusion criteria: Exclusion criteria (1) Refusing to participate in the study; (2) Previous history of asthma, chronic cough, chronic bronchitis, recent history of acute attacks; (3) Patients with extensive intraoperative abdominal adhesions who need to be separated or who need to change the surgical plan and need to switch to laparotomy; (4) Postoperative abdominal and pelvic bleeding, abdominal infection; (5) cardiovascular and cerebrovascular accidents, formation of arterial or venous thrombosis, pulmonary infection and other postoperative complications; (6) Patients who used muscle relaxants within 30 minutes before the end of surgery

Design outcomes

Primary

MeasureTime frame
Patients recovered quality scores 24 hours after surgery;Comfort rating;

Secondary

MeasureTime frame
Mean arterial pressure,MAP;Heart rate,HR;Postoperative pain rating;Operation time;Duration of anesthesia;Recovery time;Extubation time;Time to get out of bed;Postoperative hospital stay;Incidence of cough;

Countries

China

Contacts

Public ContactMa Qigang

Lu 'an Hospital of Traditional Chinese Medicine

maqigang@126.com+86 136 9564 4101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026