Effect of preoperative smoking cessation intervention by anesthesiologists on immune function of elderly patients undergoing lung cancer surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Smoking patients aged 40-75 years old; 2. ASAI-II level; 3. Imaging shows a single nodule or mass in one lung lobe; 4. Thoracoscopic radical resection of lung cancer was performed.
Exclusion criteria
Exclusion criteria: 1. History of alcoholism and opioid abuse and allergy; 2. Refuse participants; 3. Have used or are using nicotine replacement therapy and other smoking cessation interventions; 4, emergency surgery; 5. Sinus bradycardia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Th1/Th2 levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| CD4+, CD25+ regulatory T cells;CD8+ T cells; IL-2 levels; IL-4 levels;Withdrawal symptoms and smoking cravings; | — |
Countries
CHINA
Contacts
Taian City Central Hospital