Ischemic Stroke
Conditions
Interventions
Group 1:Received acupuncture treatment and basic treatments during the 2-week observation period.
Group 2:No acupuncture treatment during the 2-week observation period and only basic treatment.
Healthy control group:No intervention
Sponsors
First Teaching hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patient group: (1) Meet the above diagnostic criteria; (2) Age =18 years old, gender is not limited; (3) Ischemic stroke within 14 days of onset; (4) MRI suggested that the infarct foci were located in the region of the unilateral basal ganglia; (5) The patient had unilateral limb dyskinesia and the manual muscle testing grade 1 to 4; (6) Right-handed; (7) Signed informed consent. 2. Healthy people group: (1) Age and sex were matched to the patient group, age may go up or down by 1 year, right-handed; (2) Those who have been confirmed to be within the range of physical health by health checkup, without organic and significant functional diseases, and with normal limb motor function; (3) There was no previous family history of psychiatric or neurologic genetic disorders; (4) No stimulant medications have been taken in the last 2 months; (5) Signed informed consent.
Exclusion criteria
Exclusion criteria: Patient group. (1) Those with other causes of limb dysfunction, such as limb movement dysfunction caused by claudication, osteoarthritis, rheumatoid arthritis, gouty arthritis, and so on, which were combined before treatment. (2) Those who are unable to complete MRI scanning (e.g. suffering from claustrophobia, surgically implanted metal devices, etc.); (3) Those who are currently enrolled or have been enrolled in other clinical studies that have not yet been completed for more than three months; (4) Those with language, cognitive, and neglect disorders and audiovisual disabilities that impede communication; those with a history of neurological disorders, such as multiple sclerosis and multiple system atrophy; and those with a history of psychiatric disorders, such as depression, anxiety, mania, etc., and severe impairment of cardiac, hepatic, and renal; (5) Pregnant and lactating women. Healthy group: (1) Those with unstable vital signs; (2) Those with a history of neurological disorders, such as multiple sclerosis, multiple system atrophy, etc.; those with a history of psychiatric disorders, such as depression, anxiety, mania, etc.; and severe impairment of cardiac, pulmonary, hepatic, and renal; (3) Those who are unable to complete MRI scanning (e.g., suffering from claustrophobia, surgically implanted metal devices, etc.); (4) Those who are currently enrolled or have been enrolled in other clinical studies that have not yet been completed for more than three months; (5) Those with speech, cognitive, or neglect disorders and those with audiovisual disabilities that impede communication; (6) Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multimodal functional magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Simplified Fugl-Meyer assessment scale (FMA);National Institute of Health stroke scale(NIHSS);EuroQol Five Dimensions Questionnaire (EQ-5D) ;Modified Rankin Scale (MRS); | — |
Countries
China
Contacts
Public ContactXiaoyu Dai
First Teaching hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed