Crohn's disease
Conditions
Interventions
experimental group 1:endoscopic balloon dilatation combined with low concerntration autologous platelet-rich plasma (PRP) injection
experimental group 2:endoscopic balloon dilatation combined with hign concerntration autologous platelet-rich plasma (PRP) injection
historical control:NA
Sponsors
The Sixth Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: ? Diagnosed as CD; ? Stenosis of the colon was found during colonoscopy, and surgery was not considered for the time being; ? Imaging stenosis was found, that is, CTE suggested stenosis with proximal intestinal dilatation >3cm; ? Narrow length <5cm; ? The patients agreed to undergo endoscopic balloon dilatation and voluntarily signed the informed consent to participate in this study, and were capable of complying with the agreement.
Exclusion criteria
Exclusion criteria: ? The patient has contraindications for endoscopic therapy, such as coagulation disorder, severe cardiopulmonary dysfunction, active bleeding, and inability to cooperate. ? Deep and large active ulcer was found in the stenosis; ?< 18 years old; ? Foreign patients; ? Patients with a history of malignant tumors, including melanoma (except local skin cancer); ? Pregnant or nursing patients; ? Patients who could not be followed at all nodes of the primary outcome indicator; Other diseases that researchers believe could put patients at risk; ? Other diseases that researchers believe could put patients at risk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| restenosis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in intestinal ultrasound;Proportion of surgery; | — |
Countries
China
Contacts
Public ContactYi Lu
The Sixth Affiliated Hospital, Sun Yat-sen University
Outcome results
None listed