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Clinical effect of deep frozen allogeneic bone for bone augmentation in jaw bone defects

Clinical effect of deep frozen allogeneic bone for bone augmentation in jaw bone defects

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078293
Enrollment
Unknown
Registered
2023-12-04
Start date
2023-11-30
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lack of teeth

Interventions

Tooth extraction site preservation group:Minimally invasive extraction of single anterior or posterior teeth without preservation value under local anesthesia, removal of granulation tissue in the ext
Maxillary sinus elevation group:The elevated sinus floor mucosa is implanted with FFA bone graft material, and the implant is also implanted simultaneously. The surgical area is routinely sutured
Maxillary sinus external elevation group:Implantation of FFA bone graft material in the raised posterior sinus floor area
Large area horizontal bone augmentation group:After preparing a nourishing hole in the jawbone defect area, deep-frozen allogeneic bone fragments or blocks are placed, fixed with titanium screws, and
Vertical bone augmentation group:Placement of customized bone rings and simultaneous implantation of implants to fix the bone rings

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) The patient has teeth that cannot be preserved and needs to be extracted for delayed implant restoration. The extraction site should be preserved by site preservation surgery; (2) For patients with missing posterior teeth and insufficient sinus crest distance who require maxillary sinus augmentation or external augmentation surgery for implant repair, the sinus floor augmentation surgery area needs to be filled with bone filling materials; (3) Single anterior tooth missing, with vertical bone defects at the missing site requiring bone augmentation surgery; (4) Patients with multiple consecutive missing teeth and large horizontal and/or vertical bone defects that require bone augmentation surgery. (5) Age = 18 years old, regardless of gender; (6) Good oral hygiene conditions; (7) Do not smoke or consume less than 10 cigarettes per day, and do not drink excessively; (8) Good overall condition, assessed to be able to tolerate surgery; (9) Signed the Informed Consent Form.

Exclusion criteria

Exclusion criteria: (1) Any systemic disease that may have surgical contraindication, such as uncontrolled diabetes, hypertension, immunosuppression, coagulation dysfunction, radiotherapy, chemotherapy, alcohol or drug abuse, oral and/or intravenous bisphosphonates (2) Poor oral hygiene or inability to maintain oral hygiene according to medical advice (3) Smokers>10 cigarettes per day or alcoholics (4) Patients with active periodontitis who do not receive basic periodontal treatment (5) pregnant or lactating women (6) Patients who cannot tolerate implant surgery

Design outcomes

Primary

MeasureTime frame
Postoperative bone augmentation level ;

Secondary

MeasureTime frame
The situation of routine postoperative complications;

Countries

China

Contacts

Public ContactLinhong Wang

Zhejiang Provincial People’s Hospital

wanglinhong@hmc.edu.cn+86 139 8946 3992

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026