outlet obstructive constipation (OOC)
Conditions
Interventions
Sponsors
Army Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 18–75 years of age; Meets Rome IV diagnostic criteria for functional constipation; Meets the typical symptoms of constipation with outlet obstructive constipation (OOC) (e.g., feeling of incomplete bowel movement, difficulty in defecation, sensation of anal swelling) and the results of defecography and anal manometry; Understand and complete relevant questionnaires; Follow the research protocol and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Taken antibiotics, probiotics, prebiotics, synbiotics, proton pump inhibitors, or received fecal transplants in the last 2 months; Diagnosis of megacolon, irritable bowel syndrome, inflammatory bowel disease, etc; The history of pelvic surgery or colorectal resection; Pregnant women and patients with malignant tumors; Taking medications that may affect bowel movements (e.g., antidepressants, antispasmodics, and opioids, but not hypnotics).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fecal flora;Fecal metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| Constipation Score of Wexner;PAC-QOL;ODS Score;SAS;SDS; | — |
Countries
China
Contacts
Public ContactTong Weidong
Army Medical Center
Outcome results
None listed