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A pragmatic randomized controlled trial of the efficacy and safety of mechanical thread compression in the treatment of atherosclerosis

A pragmatic randomized controlled trial of the efficacy and safety of mechanical thread compression in the treatment of atherosclerosis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078284
Enrollment
Unknown
Registered
2023-12-04
Start date
2023-12-04
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerosis

Interventions

Experiment group:Mechanical compression technique
Control group:Anti-platelet and lipid-lowering

Sponsors

Xiyuan Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) meet the diagnostic criteria of carotid atherosclerotic plaque (carotid IMT=1.5mm) and the plaque is relatively stable, with stenosis < 50%. (2) age between 18-65 years old, regardless of gender; (3) previous history of coronary heart disease, or clinical manifestations such as chest tightness and chest pain; (4) All patients volunteered to participate in the study and signed informed consent.

Exclusion criteria

Exclusion criteria: (1) complicated with cardiovascular and cerebrovascular diseases in the acute stage; (2) carotid plaque ulcer requiring surgery or intervention; (3) patients with lower limb trauma and limited mobility; (4) pregnant, lactating women, or those who want to give birth in the past three months; (5) poor control of blood lipids, blood pressure, and blood glucose in the past three months; (6) patients with fractures in the past three months; (7) other patients that the investigator considers inappropriate to participate in the clinical study.

Design outcomes

Primary

MeasureTime frame
Carotid intima-media thickness;

Secondary

MeasureTime frame
Carotid atherosclerosis score;Carotid plaque length × thickness (longitudinal section);blood fat ;

Countries

China

Contacts

Public ContactGao Rui

Xiyuan Hospital, China Academy of Chinese Medical Sciences

ruigo@126.com+86 139 1109 7756

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026