Subacute cerebral Infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)Patients eligible for this study are aged 18 years or older and no more than 80 years old; (2)Patients have experienced their first stroke within 1 to 3 weeks 28 without prior rehabilitation; (3)Patients possess a confirmed diagnosis of a first-ever unilateral MCA-territory IS via head CT and MRI; (4)Patients exhibit an initial upper-limb function of Brunnstrom stage II-IV; (5)Patients demonstrate general cognitive abilities (MMSE > 21); (6)Patients provide voluntary informed consent.
Exclusion criteria
Exclusion criteria: (1)Patients meeting any of the following criteria will be excluded: evidence of cardioembolic stroke, brain hemorrhage on CT, arteriovenous malformation, arteriovenous fistula, or aneurysm; (2)A history of intracerebral hemorrhage, brain tumor, or malignancy; (3)Sustained hypertension (SBP > 180mmHg or DBP > 100mmHg); (4)Severe symptomatic peripheral vascular disease; (5)Coexisting systemic diseases such as renal failure (creatinine > 300µmol/L), cirrhosis, or thrombocytopenia (platelet count < 100,000/mm3); (6)Severe dementia or psychosis; (7)Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fNIRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| fugl-Meyer;MMSE;ACE-III;Berg;The Barthel index of ADL; | — |
Countries
China
Contacts
The First Affiliated Hospital,Sun Yat-sen University