Polycystic Ovary Syndrome
Conditions
Interventions
Intervention group (Group TRF):Subjects in the TRF group were instructed to adhere to a strict 8 hour time-restricted eating for 12 weeks, while also regularly taking drospirenone and ethinylestradiol
Control group (Group COC):Regularly taking drospirenone and ethinylestradiol II for 12 weeks
Sponsors
The First People's Hospital of Foshan
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Female aged 18-40 years; 2. Women diagnosed with PCOS according to Rotterdam criteria; 3. Sign the informed consent voluntarily and be willing to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Accompanied by coexisting endocrine disorders; 2. Individuals who had received corticosteroid treatment within the past 12 weeks; 3. Taking medications that may impact glucose and lipid metabolism, such as insulin, glyburide, indomethacin, phentolamine, furosemide, phenytoin sodium, cortisone, etc., within the last month; 4. Concomitant with conditions affecting glucose and lipid metabolism like thyroid dysfunction, asthma, hypertension, diarrhea, inflammatory bowel disease (IBD), intestinal stress syndrome (ISS), gastrointestinal surgery etc.; 5. Smokers and alcohol consumers; 6. Uncontrolled psychiatric disorders (including a history of hospitalization for mental illness); 7. Currently using any medication targeting or known to affect appetite; 8. Presently enrolled in weight loss or weight management programs/courses; 9. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spontaneous ovulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum glucose;Serum insulin;Triglyceride;Cholesterol;High-density lipoprotein;Low-density lipoprotein;Estradiol;Progesterone;Follicle stimulating hormone;Luteinizing hormone;Total testosterone;Prolactin;Uric Acid;Creatinine;Weight;Waist-hip ratio; | — |
Countries
China
Contacts
Public ContactZhu Minshan
The First People's Hospital of Foshan
Outcome results
None listed