Lung cancer and digestive tract tumors
Conditions
Interventions
I group:PEEP was maintained at 6 cmH2O until the end of surgery.
II group:Individualized PEEP titration was performed in the group of individualized PEEP combined with pulmonary retention strategy (Group II) after induction of anesthesia. RM was performed before ea
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Patients who plan to undergo elective laparoscopic lower abdominal surgery; 2) Catalan surgical patient respiratory risk (ARISCAT) score =26; 3) The operation requires at least 2 hours of general anesthesia; 4) Invasive arterial pressure monitoring is expected as part of routine intraoperative monitoring.
Exclusion criteria
Exclusion criteria: 1) A history of lung or upper respiratory tract infection in the past 2 weeks; 2) Severe lung disease; 3) Thoracic malformations or a history of thoracic surgery; 4) Pleural effusion; 5) Neuromuscular dysfunction; 6) ASA grade =IV; 7) Serious cardiovascular system diseases (congenital heart disease, etc.); 8) Severe hepatic and renal insufficiency (serum creatinine >186 µmol/L, bilirubin >20 µmol/L or plasma albumin <30 g/L).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications;Pulmonary ultrasound score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood gas analysis;Ventilator parameters;Incidence of PPCs within 7 days after surgery, QoR-15 recovery quality score on the 3rd day after surgery, use of vasoactive drugs, unplanned ICU stay rate, length of hospital stay, pleural effusion, ARDS, intraoperative hypoxemia, arrhythmia; | — |
Countries
China
Contacts
Public ContactJiru Zhang
Affiliated Hospital of Jiangnan University
Outcome results
None listed