Oral and maxillofacial head and neck tumors
Conditions
Interventions
Experimental group:Routine nursing + chewing rehabilitation intervention, 20 minutes three times a day
Control group:Routine nursing
Sponsors
Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University, School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-70 years; (2) Men and women are not limited; (3) mandibular benign tumors or lesions requiring mandibular amputation; (4) Normal blood routine, coagulation function, liver function, kidney function and ECG within 1 week before surgery (hemoglobin > 80 g/L; The absolute neutrophil count was > 1.5×109/L, and the platelet count was > 100 ×109/L. Bilirubin < 35 umol/L; AST or ALT < 3 x upper normal limit; Serum creatinine < 130 umol/L or creatinine clearance =50 ml/min); (5) Maxillofacial enhanced CT and panoramic film were performed 1 week before surgery; (6) No organic lesions of important organs, suitable for general anesthesia surgery; (7) Postoperative radiotherapy and chemotherapy were not required.
Exclusion criteria
Exclusion criteria: (1) Recurrence of other malignant tumors or primary tumors within five years; (2) Have a history of severe drug allergy; (3) pregnant, lactating or patients with neurological disorders; (4) Patients who have participated in other clinical trials; (5) Patients who have received anti-tumor therapy such as radiotherapy, chemotherapy and targeted drugs before surgery; (6) Mouth opening < 3.5cm; (7) contraindications associated with general anesthesia surgery (such as high blood pressure, diabetes, etc., which are difficult to control with drugs); (8) Patients with congenital immune deficiency or organ transplantation; (9) Patients with HBV, HCV, HIV, TRUST and other related diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| masticatory efficiency; visual analogue scale, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bite force measurement;QLQH&N35; | — |
Countries
China
Contacts
Public ContactGu Fen
Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University, School of Medicine
Outcome results
None listed