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Efficacy and safety of remazolam and propofol in hepatic radiofrequency ablation

Efficacy and safety of remazolam and propofol in hepatic radiofrequency ablation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078192
Enrollment
Unknown
Registered
2023-11-30
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatoma

Interventions

Control group:Propofol is used for induction and maintenance of anesthesia
Intervention group:Remazolam is used for induction and maintenance of anesthesia

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA grades 1-3, age 30-60 years, body mass index (BMI) <30kg m-2, 60 patients undergoing ultrasound-guided percutaneous radiofrequency ablation for liver cancer in the Affiliated Hospital of North Sichuan Medical College.

Exclusion criteria

Exclusion criteria: Patients with a history of hypertension, coronary heart disease, diabetes, central nervous system diseases, patients with poor cardiopulmonary function, and patients with contraindications in the use of propofol or remazolam.

Design outcomes

Primary

MeasureTime frame
Heart rate;Mean arterial blood pressure;Respiratory rate;modified observer's assessment of alert / sedation, MOAA/S;Partial pressure of end-expiratory carbon dioxide;

Secondary

MeasureTime frame
Visual analogue pain score,VAS;Duration of anesthesia;Duration of hepatic radiofrequency ablation;Recovery time;The dose of analgesic drugs;

Countries

China

Contacts

Public ContactJiang Pingping

Affiliated Hospital of North Sichuan Medical College

307174907@qq.com+86 158 8149 6034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026