Postoperative Pain after Laparoscopic Myomectomy
Conditions
Interventions
Control Group:10ml: 100mg ropivacaine 20ml in the SHP area
Treatment Group:10ml: 100mg ropivacaine 19ml + 1ml: 5mg dexamethasone 1ml in the SHP area
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing elective laparoscopic myomectomy for uterine fibroids. 2.Number of fibroids not exceeding 10. 3.ASA grade of I-III. 4.Age between 18 to 55 years. 5.Willingness to participate in the study and provide signed informed consent. 6.Not currently participating in other clinical trials.
Exclusion criteria
Exclusion criteria: 1.Presence of other gynecological diseases, such as endometriosis, adenomyosis, cervical cancer, ovarian tumor, ovarian cyst, fallopian tube disease, vulvar cancer, and pelvic/abdominal adhesion. 2.Severe neurological disorders including Alzheimer's disease, Parkinson's disease, or epilepsy, and mental disorders such as anxiety or depression. 3.A history of diabetes mellitus, smoking, or alcohol abuse. 4.Long-term use of non-steroidal drugs, opioids, or other analgesic medications. 5.Chronic use of sedatives, hypnotics, or other psychiatric drugs. 6.Treatment with systemic glucocorticoids within the 4 weeks prior to surgery. 7.Allergy to trial drugs including ropivacaine and dexamethasone. 8.Inability to cooperate with the postoperative Visual Analogue Scale (VAS) score assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| cumulative consumption of non-steroidal anti-inflammatory drugs or opioids within 48 hours postoperatively;postoperative adverse reactions;intraoperative fluid volume, urine output, and blood loss;first postoperative exhaust time;first postoperative ambulation; | — |
Countries
China
Contacts
Public ContactYing Zhang & Yingying Li
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed