Skip to content

Effect of dexamethasone combined with gastrointestinal decompression during operation on postoperative nausea and vomiting in patients with BASKA laryngeal mask positive pressure ventilation

Effect of dexamethasone combined with gastrointestinal decompression during operation on postoperative nausea and vomiting in patients with BASKA laryngeal mask positive pressure ventilation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078148
Enrollment
Unknown
Registered
2023-11-29
Start date
2023-12-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

A:Dexamethasone (0.1mg /kg) iv
B:Intraoperative gastrointestinal decompression
C:Intravenous dexamethasone (0.1 mg/kg) combined with intraoperative gastrointestinal decompression

Sponsors

Panzhihua Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.ASA Grade I-II; 2. Age 18-65 years old; 3. Body mass index of 18.5-30.0kg/m2

Exclusion criteria

Exclusion criteria: 1. Limited mouth opening (less than two fingers); 2. Throat malformation and other pathological changes; 3. Potential respiratory obstruction (e.g. trachea compression, softening, throat mass, abscess, hematoma, or infection); 4. Full eating, high intra-abdominal pressure, high risk of aspiration of vomiting reflux, history of habitual vomiting; 5. Obesity. (BMI>30 kg/m2)

Design outcomes

Primary

MeasureTime frame
Flatulence, nausea, vomiting, sore throat and hoarseness 1, 6 and 24h after surgery.;Antrum area before anesthesia induction (T0), after laryngeal mask placement (T1), and after extubation (T2);

Secondary

MeasureTime frame
Heart rate and blood pressure during entry, before intubation, after intubation, 5 minutes after intubation, before extubation, and after extubation;Mechanical ventilation time, operation time;Postoperative gastrointestinal function recovery time;Intraoperative and postoperative analgesics and anesthetics used;General information of the patient (height, weight, age, sex);

Countries

China

Contacts

Public ContactXianrong Hu

Panzhihua Central Hospital

1318508878@qq.com+86 180 9630 7257

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026