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Clinical study of intermittent theta burst stimulation for the treatment of postherpetic neuralgia

Clinical study of intermittent theta burst stimulation for the treatment of postherpetic neuralgia

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078115
Enrollment
Unknown
Registered
2023-11-29
Start date
2023-11-30
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postherpetic neuralgia

Interventions

rTMS group:rTMS treatment with a frequency of 10Hz and a total of 3000 stimuli was performed on the contralateral M1 region of the patient.The treatment cycle is 2 weeks, with 5 consecutive days per w
iTBS group: Perform iTBS treatment on the contralateral M1 area of the patient with 50Hz intra plexus, 5Hz inter plexus, and a total of 600 stimuli.The treatment cycle is 2 weeks, with 5 consecutive d

Sponsors

Hangzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: a) Conforming to the IASP diagnosis of postherpetic neuralgia; b) 50 years old or above; c) Persistent pain that persists for one month after the onset of pain; d) Visual Analog Scale (VAS) for Pain Intensity: between 3 and 9 points; e) There is no history of pain control medication adjustment within two weeks before and during the trial period; f) Able to cooperate in completing evaluations and treatments; g) Understand and be willing to participate in this clinical trial and provide a signed informed consent form.

Exclusion criteria

Exclusion criteria: a) Inability to accept iTBS or rTMS interventions (such as pacemakers); b) Individuals who suffer from severe mental illness, aphasia, and cognitive impairment due to various reasons and are unable to cooperate with rehabilitation assessment and treatment in a sitting position; c) Those with other serious diseases such as malignant tumors; d) The mRS score of the patient before this onset is = 2 points; e) Metal implantation surgery; Previous history of epileptic seizures/seizures/treatment with antiepileptic drugs; Pregnant or intending to conceive within six months; f) Individuals who have undergone craniocerebral surgery due to stroke or other reasons; g) Individuals with severe cardiopulmonary dysfunction, extreme weakness, and other unstable conditions.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
McGillpainquestionnaire;Pittsburgh sleep quality index;SDS/SAS;NLRP3;

Countries

China

Contacts

Public ContactLiang Yu

Hangzhou First People's Hospital

yuliang0601@zju.edu.cn+86 139 5716 2972

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026