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The change of fibrinolytic state in severe trauma patients and the effect of clinical intervention on it

The change of fibrinolytic state in severe trauma patients and the effect of clinical intervention on it

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300078089
Enrollment
Unknown
Registered
2023-11-28
Start date
2021-07-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma-induced coagulopathy

Interventions

Grouping based on the LY30 index in the thromboelastogram:None

Sponsors

Taicang First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) All kinds of trauma patients admitted to trauma centers, including mechanical injuries, physical injuries, etc.; (2) Systolic blood pressure < 90mmHg, GCS=8 points or triage identified as severe trauma with the risk of major bleeding.

Exclusion criteria

Exclusion criteria: (1) Injury Severe Score (ISS) 3 hours; (7) Death within 8 hours of admission.

Design outcomes

Primary

MeasureTime frame
LY30;24-hour mortality;28-day mortality ;—

Secondary

MeasureTime frame
Reaction time;kinetic time;a angle;maximum amplitude;gender;age;Time from injury to emergency department;Cause of injury;Trauma type;GCS;ISS;temperature;BP;HR;HB;HCT;Lac;PT;APTT;Fg;The amount of blood transfusions in 24 hours;Mechanical ventilation time;ICU stay days;Incidence of VTE;Incidence of MT;Incidence of MODS ;—

Countries

China

Contacts

Public ContactLuping Zhang

Taicang First People's Hospital

zhanglp_861017@163.com+86 158 5029 8061

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026