primary biliary cholangitis
Conditions
Interventions
Non-portal hypertension group:No
Sponsors
Beijing YouAn Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? Patients with primary biliary cholangitis, both male and female; ?Age: 18~65 years old; ? The diagnosis is made by the 2021 PBC Diagnosis and Treatment Guideline; ?Child-Pugh score ?6 or early PBC diagnosis confirmed by liver biopsy (Ludwig pathological stage I and II); ?There were previously frozen serum samples for the detection of cytokines; ? Patients can cooperate with monitoring and sign informed consent.
Exclusion criteria
Exclusion criteria: ?Combined with Hepatitis B surface antigen positive, hepatitis C antibody positive, drug-induced liver injury; ?Combined with autoimmune hepatitis, non-alcoholic steatohepatitis and alcoholic liver disease; ?Combined with systemic sclerosis, systemic lupus erythematosus, psoriasis, sjogren's syndrome and other diseases; ?Combined with organ failure, such as heart failure, respiratory failure, renal failure, etc; ?Combined with malignant tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACA antibody; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum IL-17; | — |
Countries
China
Contacts
Public ContactJuan Zhao
Beijing YouAn Hospital, Capital Medical University
Outcome results
None listed