Type 2 diabetic kidney injury disease
Conditions
Interventions
Sponsors
2nd Affiliated Hospital Hainan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: A total of 150 inpatients and outpatients in the Second Affiliated Hospital of Hainan Medical University from January 2022 to August 2023 were selected and diagnosed with T2DM according to the ADA diagnostic criteria in 2021. The patients were communicated with to obtain their consent, and corresponding urine samples were collected. According to ACR, 50 patients were divided into normal albuminuria (NA) group, with ACR 300mg/24h.
Exclusion criteria
Exclusion criteria: (1) Type 1 and other types of diabetes mellitus, gestational diabetes mellitus, acute hyperglycemic disorders; (2) Patients with acute and chronic liver diseases and essential hypertension; (3) Patients with thyroid diseases such as thyroid dysfunction and thyroid cancer; (4) Patients with urinary calculi, gross hematuria, massive albuminuria, acute kidney injury and end-stage renal disease; (5) Patients with acute and chronic cardiac dysfunction, atrial fibrillation and other arrhythmias; (6) Patients with acute and chronic infectious diseases, autoimmune diseases and malignant tumors; (7) Patients who have recently undergone major operations; (8) Patients with anemia and other blood system diseases; (9) Patients who have recently taken hormones, anti-platelet aggregation and other drugs to change blood flow status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACR (Urinary microalbumin to creatinine ratio);MA (microalbumin);TRU (transferrin);IgG (Immunoglobulin G);a2-mG (a2 macroglobulin);a1-MG (Urinary a1-microglobulin);ß2-MG (Urinary beta-2-microglobulin);RBP (Retinol-binding protein);NAG (Urinary n-acetylß-D-aminoglycosidase);Neutrophil gelatinase-associated lipid carrier protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biochemical indicators;General baseline data; | — |
Countries
China
Contacts
Public ContactBing Li
The Second Affiliated Hospital of Hainan Medical College
Outcome results
None listed