skin permeability
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy adult men and women aged 18-60; 2. Have not used products containing sunscreen in two weeks, including sunscreens, creams, lotions and BB cream with SPF; 3. Willing to participate in the experiment, and able to complete the skin test as required during the whole research process; 4. Have read and signed the informed consent before the study begins; 5. In good health at the time of the test; 6. BMI is 18.5-29.9; 7. No planned pregnancy within 1 month before and after the test; 8. Subjects self-reported non-sensitive skin; 9. Can complete the prescribed content according to the requirements of the test plan.
Exclusion criteria
Exclusion criteria: 1. Patients with serious systemic disease who are currently using systemic or local topical corticosteroids, retinoic acid, vasoconstrictors, antibiotics, anti-inflammatory drugs, etc., or within one month before the start of this study; 2. Patients with severe allergic diseases or who have had cosmetic allergies in the last 1-2 years; 3. Allergic history of daily use of sunscreen products; 4. Pregnant, breastfeeding or planning to become pregnant; 5. Oral contraceptives (nearly 3 months and throughout the study period); 6. Allergic to alcohol; 7. The test area has a large area of acne, tattoos and other skin conditions that affect the test results; 8. There is A history of skin or other medical conditions that affect the results of the test and other conditions that prevent the use of the test sample; 9. Have participated in other clinical trials at present or within 3 months before the start of this study; 10. There are other conditions that the investigator deems unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sunscreen content in Blood; | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety Evaluation; | — |
Countries
China
Contacts
Huashan Hospital