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Prospective, randomized, controlled study of endoscopic ultrasound-guided transgastric/transduodenal placement of metal stents combined with nasocystic drainage for the treatment of pancreatic walled-off necrosis.

Prospective, randomized, controlled study of endoscopic ultrasound-guided transgastric/transduodenal placement of metal stents combined with nasocystic drainage for the treatment of pancreatic walled-off necrosis.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078044
Enrollment
Unknown
Registered
2023-11-28
Start date
2021-08-24
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Walled-off pancreatic necrosis

Interventions

Nasal drainage tube placement group :Metal stent implantation + Nasocystic drainage
Metal stent placement group:Metal stent placement

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Age of 18-80 years old, both sexes; 2) WON adjacent to the gastric or duodenal wall on CT or MRI; 3) Coexisting with one of the following symptoms; a. There are obvious compression symptoms, including abdominal pain/bloating, anorexia/early satiety, nausea/vomiting, jaundice and other symptoms b. Persistent fever, clinical suspicion or confirmed walled-off necrosis complicated with infection (WBC/CRP increased, CT showed bubbles in the cavity, etc.) c. Rapid enlargement of the lesion in a short period of time 4) signed informed consent

Exclusion criteria

Exclusion criteria: 1) Coagulopathy (INR>1.5) and thrombocytopenia (1.0cm from gastrointestinal wall; 5) patients with severe heart and lung diseases who cannot tolerate surgery; 6) pregnant or lactating patients; 7) patients who refused to sign informed consent form

Design outcomes

Primary

MeasureTime frame
Blood cell analysis;C-reactive protein;Procalcitonin;Interleukin-6;

Secondary

MeasureTime frame
Cure rate;Duration of stent placement;Endoscopic debridement times ;The proportion requiring further percutaneous drainage or conversion to surgery;

Countries

China

Contacts

Public ContactZhu Yin

The First Affiliated Hospital of Nanchang University

zhuyin27@sina.com+86 139 7084 1464

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026