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An Exploratory Study of prevention of Medication-Related Osteonecrosis of the Jaw after tooth extraction in patients with intravenous medication history of bisphosphonates..

An Exploratory Study of prevention of Medication-Related Osteonecrosis of the Jaw after tooth extraction in patients with intravenous medication history of bisphosphonates.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078023
Enrollment
Unknown
Registered
2023-11-27
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medication-Related Osteonecrosis of the Jaw

Interventions

test group:minimally invasive extraction and CGF application
control group:minimally invasive extraction

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. have received or being receiving intravenous injection of BPs 2. in generally good condition (ASA I class or II class) 3. have hopeless tooth 3. after periodontal fundamental treatment 4. volunteer to participate and signed the consent form

Exclusion criteria

Exclusion criteria: 1. somker 2. pregnant or lactating women 3. history of irradiation of head-neck region 4. long course of taking corticosteroids and immunosuppressor 5. acute infection of tooth 6. already have MRONJ manifestation

Design outcomes

Primary

MeasureTime frame
Medication-Related Osteonecrosis of the Jaw;—

Secondary

MeasureTime frame
width of the gingival fissure;area of the gingival fissure;area of the exposed alveolar ridge;Visual analog pain score;—

Countries

China

Contacts

Public ContactYe Peng

Beijing Hospital

derrickye@yeah.net+86 10 8513 3402

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026