adenomyosis
Conditions
Interventions
Intramuscular lesion group:NA
External myomyotic disease group:NA
control group:NA
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) Severity of disease: diffuse adenomyopathy with severe dysmenorrhea, blurred vision score =7, need analgesic drugs; Diffuse lesions with a uterus = 70 days gestational size (volume >100cm3) involving more than 80% of the anterior and/or posterior wall muscles, or a thickened single layer of more than 6cm. In diffuse uterine myomatosis, anemia is caused by increased menstrual volume, hemoglobin is less than 80g/L, and the number of fibroids is more than 50. 2) Age and infertility history: age 20-45 years old, married, have fertility requirements; Infertility for more than 2 years, have tried a variety of methods to assist pregnancy failed (note: ovarian reserve function is normal, AMH =1.09, do not combine uterine malformation and intrauterine model injury adhesion syndrome and other uterine infertility assessment; Decreased AMH or combined with other infertility factors were included, but fertility analysis was not performed.) 3) Meet the above inclusion criteria and voluntarily undergo PUSH surgery without surgical contraindications.
Exclusion criteria
Exclusion criteria: 1) Patients with serious medical and surgical diseases can not tolerate surgery, in any systemic inflammation in the acute phase, pregnancy, breastfeeding or accompanied by malignant tumors; 2) No study was included if any of the above inclusion criteria were not met.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multiomics evaluation of ovarian function; | — |
Countries
China
Contacts
Public ContactRuifang Wu
Peking University Shenzhen Hospital
Outcome results
None listed