Skip to content

Pneumoperitoneo-pressure-directed PEEP setting in elderly patients undergoing laparoscopic abdominal surgery——A multicenter prospective randomized controlled study

Pneumoperitoneo-pressure-directed PEEP setting in elderly patients undergoing laparoscopic abdominal surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300078020
Enrollment
Unknown
Registered
2023-11-27
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications

Interventions

Sponsors

The First Medical Center of the PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1.ASA grade I-II 2. Age > 60 years old; 3.18kg/m²=BMI=35kg/m²; 4. Patients undergoing abdominal endoscopy under elective general anesthesia 5. Operation pneumoperitoneum time is not less than 2h.

Exclusion criteria

Exclusion criteria: 1. Those who refuse to participate in the experiment and do not sign the informed consent; 2. The patient had symptoms of upper respiratory tract infection or pulmonary infection in the past 4 weeks, and chest X-ray indicated pneumonia; 3. Diseases affecting thoracic and lung compliance, such as chicken breast, funnel chest, chest trauma and surgical history, chronic obstructive emphysema, pleural effusion and acute respiratory distress syndrome; 4. History of neuromuscular dysfunction; Have serious cardiovascular events, diseases of lung, kidney and hematopoietic system; 5. Patients who had received general anesthesia 7 days before randomization; Patients with mental system diseases and cognitive disorders; Patients with a history of psychotropic or narcotic drug abuse; 6. Other circumstances in which the investigator determines that the patient is not suitable for participation in the clinical trial.

Design outcomes

Primary

MeasureTime frame
Postoperative Pulmonary Complicantions;

Secondary

MeasureTime frame
Respiratory Mechanics Parameters;Postoperative hypoxemia;Hemodynamics parameters;Pulmonary Atelectasis;

Countries

China

Contacts

Public ContactMi Weidong

The First Medical Center of the PLA General Hospital

wwdd1962@163.com+86 133 8108 2966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026