Effects of different methods of lidocaine on cough and postoperative pain after extubation of colorectal cancer

Comparison of the effects of single or continuous infusion of lidocaine on extubation period in patients undergoing gastrointestinal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300078016

Enrollment

Unknown

Registered

2023-11-27

Start date

2022-08-25

Completion date

Unknown

Last updated

2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough on extubation

Interventions

C group:None

S group:Single injection of lidocaine

P group :Continuous infusion of lidocaine

Eligibility

Sex/Gender

All

Age

40 Years to 75 Years

Inclusion criteria

Inclusion criteria: The patients were ASA?~?, 40~75 years old, BMI 18~30(kg/m2), weight 40~85 kg.

Exclusion criteria

Exclusion criteria: . Allergic history of local anesthetics . Liver insufficiency or renal insufficiency . Chronic obstructive pulmonary disease, asthma or other respiratory diseases . Poorly controlled hypertension, diabetes or heart disease . Communication barriers or inability to cooperate . Anticipated difficult airway . Patients taking angiotensin converting enzyme inhibitors . Patients with severe anemia or massive intraoperative bleeding Postoperative anastomotic fistula or postoperative bleeding and other complications

Design outcomes

Primary

Measure	Time frame
Cough at extubation;	—

Secondary

Measure	Time frame
Pain score;Quality of recovery questionnaire 40;	—

Countries

China

Contacts

Public ContactWeiwei Wang

The 2nd affiliated hospital of haerbin medical university

wangweiwei_1980@126.com+86 188 4575 8923

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026