None
Conditions
Interventions
Test group:Set different PIEB interval times
Sponsors
Peking University First Hospital Ningxia Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years old; 2. Primipara with singleton, full-term, cephalic pregnancy and planned vaginal delivery; 3. American Society of Anesthesiologists (ASA) grade II-III; 4. Cervical dilation < 5 cm; 5. Agree to receive intrathecal labor analgesia.
Exclusion criteria
Exclusion criteria: 1. Contraindications to intraspinal puncture (previous history of central nervous system infection, history of spinal and intraspinal diseases, systemic infection, skin or soft tissue infection at the puncture site, coagulation dysfunction); 2. Gestational hypertension; 3. Body mass index (BMI) >= 35kg/m2; 4. Patients who received sedatives within 4 hours before epidural analgesia; 5. Allergy to local anesthetics or dexmedetomidine; 6. Prenatal bradycardia (HR < 60 bpm) or hypotension (SBP < 90mmHg); 7. Investigators or attending physicians deem it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The 90% effective interval time of 0.075% ropivacaine and 0.4 µg/mL dexmedetomidine 8 mL by dural puncture technique for epidural labor analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Plane of sensory block;Motor block of the lower limbs;Maternal adverse outcomes;Maternal satisfaction; | — |
Countries
China
Contacts
Public ContactQiaoli Yin
Peking University First Hospital Ningxia Women's and Children's Hospital
Outcome results
None listed