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Effect of ultrasound-guided femoral nerve combined with femoral artery block on tourniquet response in lower limb surgery

Effect of ultrasound-guided femoral nerve combined with femoral artery block on tourniquet response in lower limb surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077999
Enrollment
Unknown
Registered
2023-11-27
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lower limb surgery

Interventions

Femoral nerve combined with femoral artery block group:Femoral nerve combined with femoral artery block
Simple femoral nerve block group:femoral nerve block

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients who need to use tourniquet during elective lower limb surgery in our hospital, such as knee arthroscopy, internal fixation of tibia and fibula, and knee joint replacement, can be enrolled in this study only if they meet the following conditions: 18 years old = age = 80 years old, regardless of gender; ASA is classified as I-III; 18 kg/m2=BMI=30kg/m2 Denied having serious cardio-cerebrovascular diseases; Sign the informed consent form (ICF) voluntarily, and are willing to abide by and expected to complete the test according to the requirements of the test protocol.

Exclusion criteria

Exclusion criteria: (1) The patient has chronic pain and takes opioid analgesics for a long time; (2) Blocking site infection; (3) Allergic to local anesthetic; (4) Combined with ischemic heart disease or uncontrolled hypertension, (5) tourniquet contraindication (peripheral neuropathy, peripheral vascular disease, etc.), (6) combined with mental disease, language disorder, inability to cooperate and serious hearing or visual impairment; (7) Long-term alcohol or drug dependence; (8) The accumulated time of tourniquet inflation is less than 45 minutes or more than 120 minutes; (9) Other conditions determined by the researcher to be unsuitable for selection.

Design outcomes

Primary

MeasureTime frame
Blood pressure fluctuation at various time points after tourniquet inflation;

Secondary

MeasureTime frame
Dosage of nicardipine and esmolol during operation;Pain score and analgesic relief at each time point after surgery;The occurrence of postoperative nausea, vomiting, delirium and other adverse reactions;

Countries

China

Contacts

Public ContactHu Ling

The First Affiliated Hospital of University of Science and Technology of China

hing1210@163.com+86 139 5696 8140

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026