Anesthesiology
Conditions
Interventions
Ciprofol group:Anesthesia induced intravenously administered ciprofol and etomidate, and maintained intravenously administered ciprofol
NS group:Anesthesia induced intravenously administered normal saline and etomidate, and maintained intravenously administered ciprofol
Sponsors
First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-60, ASAI-III grade, who undergo elective intubation and general anesthesia, are scheduled to be sent to a recovery room for resuscitation and tracheal catheter removal after surgery.
Exclusion criteria
Exclusion criteria: 1.Severe hypertension (systolic blood pressure = 180mmHg, or diastolic blood pressure = 110mmHg); 2.Tachycardia (heart rate>100 beats/min); 3. Coronary heart disease; 4. Difficult airway; 5.Adrenal cortical dysfunction; 6. Patients with severe heart, liver, lung, or kidney diseases; 7. Severe anemia, shock, metabolic disorders, electrolyte disorders; 8. Severe infections (sepsis, sepsis, brain abscess); 9. Pregnant women; 10. Patients who are unable to communicate; 11. Patients with delayed gastric retention or gastric emptying; 12. Patients who abuse hormones or anesthetic analgesics; 13. Individuals who are allergic to the studied medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive rate of cardiovascular reaction during tracheal intubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| vital signs;The total amount of vasoactive drugs used during anesthesia induction and maintenance periods;Total amount of anesthetic drugs;Anesthesia and surgical related time; | — |
Countries
China
Contacts
Public ContactXuehai Guan
First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed