Unexplained Recurrent Implantation Failure
Conditions
Interventions
IR group, non-IR group, with metformin group and without metformin group :none
Sponsors
Guangxi Reproductive Medical Center, the First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Age 20-40 years old; (2) Diagnosed as RIF (embryo implantation failure frequency = 3 times); (3) BMI less than 30 kg/m2; (4) Both male and female chromosomes are normal;
Exclusion criteria
Exclusion criteria: 1) Chromosomal abnormalities in either party (male or female). 2) Individuals with uterine endometrial lesions (history of intrauterine adhesions, untreated endometrial polyps or submucosal fibroids, past history of uterine endometrial tuberculosis). 3) Reproductive tract anomalies. 4) Individuals with tubal hydronephrosis who have not undergone tubal ligation. 5) Adenomyosis. 6)Autoimmune system diseases. 7)Other endocrine disorders (abnormal thyroid function), hyperprolactinemia. 8)Patients with a tendency for thrombus formation. 9)Incomplete data and loss to follow-up patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| General situation and clinical observation indicators;live birth rate;pregnancy loss rate; | — |
Countries
China
Contacts
Public ContactYihua Yang
Guangxi Reproductive Medical Center, the First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed