Breast Cancer
Conditions
Interventions
Control group:erector spinal muscle block
Experimental group:modified intercostal nerve block
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients underwent modified radical mastectomy in our hospital; 2.aged 18 to 65 years old; 3.ASA I-III; 4.weight 40-80kg.
Exclusion criteria
Exclusion criteria: 1.Patients with contraindications to regional block technique(allergy to local anesthetic, infection around puncture site and coagulation disorder); Patients with peripheral neuropathy or sensory abnormalities in the nerve innervated skin area at the puncture site/site that needs to be blocked; 2.Preoperative use of opioid drugs; 3.Patients with heart failure, severe arrhythmia, and severe liver and kidney disease; 4.BMI>35kg/m2; 5.patients with not accurate in evaluating dysfunction postoperative analgesia; 6.Mental Disorders (depression, mania, schizophrenia, or a history of antipsychotic use); 7.Failure to sign an informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain scores of rest and movement at 6h; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of intraoperative anesthetics,vasoactive drugs and infusion amount;Postoperative hospital stay;Hemodynamics;Postoperative adverse reactions;operation time?anesthesia time;pain scores of rest and movement at 0h,3h,12h,24h after Postoperative awake2;Postoperative Quality of Recovery Score in 24h;The amount of remedial drugs used after surgery; | — |
Countries
China
Contacts
Public ContactGuanghong Xu
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed