Gastric Cancer Tumor
Conditions
Interventions
Experimental group:Patients in the naloxone group were treated with open venous channels and PCIA pump infusion of 0.05 from 3 days before surgery to 5 days after surgery 0.05ug/kg.h of naloxone
Postoperative composite 0.04ug/kg.h(calculated at 48 hours) sufentanil
control group:Non naloxone group received 0.04 PCIA pump injection after surgery0.04ug/kg.h (calculated at 48 hours) sufentanil. Set the PCIA dosage to 2 mL, lock in time to 20 minutes, and background
Sponsors
Shandong First Medical University Affiliated Cancer Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Class I-II, age = 75 years old 2. Patients planning to undergo partial or total gastrectomy
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart and lung diseases were excluded from the group. 2. Patients with severe liver and kidney dysfunction were excluded from the group. 3. Allergies to naloxone were excluded from the group. 4.Patients with opioid addiction or abuse, as well as dizziness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NK cell;CD4+T cells; | — |
Secondary
| Measure | Time frame |
|---|---|
| CD8+T cells;Peripheral blood leukocyte count;; | — |
Countries
Chian
Contacts
Public ContactMin Xiangzhen
Shandong First Medical University Affiliated Cancer Hospital
Outcome results
None listed