type 2 diabetes
Conditions
Interventions
Metformin treatment for the thick tongue coating group, metformin treatment for the thin tongue coating group
:Metformin treatment
microbiota transplantation for the thick tongue coating group, microbiota transplantation for the thin tongue coating group
:Intestinal flora transplantation
metformin combined with microbiota transplantation for the thick tongue coating group, metformin combined with microbiota transplantation for the thin tongue coating group.:metformin combined with mic
Sponsors
The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: ? Meets the above-mentioned diagnostic criteria of both Chinese and Western medicine. ? Diagnosed with diabetes for at least 2 years. ? Age between 18 and 70 years old. ? Has not used antibiotics or probiotics within the past month. ? Complete medical records, able to freely extend the tongue for examination. ? Stable blood sugar control plan in the past three months. ? Conscious and has good comprehension and language expression abilities, able to successfully complete the questionnaire. ? Sufficient communication with the patient or their family members, and their willingness to participate. ? Sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? Type 1 diabetes, gestational diabetes, secondary hyperlipidemia, obesity, cardiovascular and cerebrovascular diseases, malignant tumors, and a history of chronic infectious diseases. ? Individuals with significant illnesses such as severe bleeding. ? Patients with acute or chronic gastrointestinal disorders. ? Individuals with mental illnesses. ? Pregnant or lactating women. ? Substance abusers. ? Individuals with a history of binge eating, fasting, or eating disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting Blood Sugar;Postprandial 2-hour Blood Sugar;Glycated Hemoglobin ;Intestinal Microbiota Analysis;complete blood count;comprehensive metabolic panel;C-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lipid Level Testing;electrocardiogram;urinalysis;stool analysis;kidney function;24-hour urine protein quantification;microalbuminuria (MAU) levels; | — |
Countries
China
Contacts
Public ContactCandong Li
The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine
Outcome results
None listed