Dexamethasone combined with Dexmedetomidine Prolonged the Duration of Analgesia for Interscalene Brachial Plexus Block

Dexamethasone combined with Dexmedetomidine as an adjunct to ropivacaine Prolonged the Duration of Analgesia for Interscalene Brachial Plexus Block

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300077921

Enrollment

Unknown

Registered

2023-11-23

Start date

2023-12-01

Completion date

Unknown

Last updated

2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group D:Dexamethasone as an adjunct to ropivacaine is used for ultrasound-guided interscalene brachial plexus block

Experimental group Y:Dexmedetomidine as an adjunct to ropivacaine is used for ultrasound-guided interscalene brachial plexus block

Experimental group DY:Dexamethasone combined with Dexmedetomidine as an adjunct to ropivacaine is used for ultrasound-guided interscalene brachial plexus block

Control group C:none

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing upper extremity surgery for the first time; 2. In line with the indications of interscalene brachial plexus block; 3. ASA I-?; 4. Aged 18-75 years, gender unlimited; 5. Get informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating patients; 2. Morbid obesity (BMI>=40kg/m^2); 3. Patients with severe heart, brain, liver and kidney diseases; 4. Patients with upper limb paralysis or limb sensory and movement disorders; 5. Patients with mental illness, inability to communicate properly, or inability to correctly score VAS; 6. Patients allergic to amides local anesthetics, dexamethasone and dexmedetomidine; 7. Patients with a history of opioid or drug abuse.

Design outcomes

Primary

Measure	Time frame
duration of analgesia;	—

Secondary

Measure	Time frame
sensory block time;motor block time;time of first analgesia;resting visual analog score;visual analog score after exercise;remedial medication;	—

Countries

China

Contacts

Public ContactTang Li

Xishan People's Hospital of Wuxi

tangl0305@163.com+86 510 8240 2084

Outcome results