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Research of accurate molecular markers and auxiliary diagnosis system for early thrombosis in acute cerebral infarction

Research of accurate molecular markers and auxiliary diagnosis system for early thrombosis in acute cerebral infarction

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077911
Enrollment
Unknown
Registered
2023-11-23
Start date
2023-07-03
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

Case group:None
Healthy control group:None

Sponsors

The First Affiliated Hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 89 Years

Inclusion criteria

Inclusion criteria: Case group: 1: Age =18 years 2: Patients with acute ischemic stroke confirmed to have onset within 24 hours through CT/MRI are diagnosed in accordance with the "2019AHA/ASA Guidelines for Early Management of Acute Ischemic Stroke" and the "China Guidelines for Early Endovascular Interventional Diagnosis and Treatment of Acute Ischemic Stroke 2022" 3: Informed consent signed by the patient, their immediate family members, or their authorized agents Control group: 1: Healthy individuals who undergo health examinations at the physical examination center of our hospital during the same time period and are matched with the group of acute ischemic stroke patients based on age, gender, and body mass index; 2: No previous underlying diseases, no known bleeding disorders, liver or kidney diseases, cancer, surgical history, or thrombotic events within the past 3 months, and no antiplatelet or anticoagulant treatment received; 3: The patient signed the informed consent form

Exclusion criteria

Exclusion criteria: 1: mRS =2 points before the onset of this disease 2: Patients with moderate-to-severe mental disorders and dementia affecting the assessment of neurological functio 3: History of surgery within 3 months, severe acute or chronic infection, autoimmune disease, malignancy 4: A woman who is pregnant or breastfeeding 5: Patients with hemorrhagic stroke, no ischemic stroke, or unknown ischemic stroke had ischemic stroke

Design outcomes

Primary

MeasureTime frame
Neutrophil functional differential protein;

Secondary

MeasureTime frame
Imaging;Time from onset to thrombectomy;The cause of blood embolus;

Countries

China

Contacts

Public ContactXu Anding

The First Affiliated Hospital of Jinan University

TLIL@JNU.EDU.CN+86 133 9269 2160

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 4, 2026