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Absolute quantitative sequencing of oral flora in the prediction of clinical outcome after periodontal initial treatment in patients with moderate or severe periodont

Absolute quantitative sequencing of oral flora in the prediction of clinical outcome after periodontal initial treatment in patients with moderate or severe periodontitis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077894
Enrollment
Unknown
Registered
2023-11-23
Start date
2023-11-23
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Case series:NA

Sponsors

Shanghai Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Diagnosed as stage III or IV periodontitis according to the 2018 consensus classification of periodontal and peri-implant diseases and conditions; ? Age 20-60 years; ? =16 remaining teeth; (iii) =2 non-adjacent teeth with adjacent attachment loss detected, maximum CAL =5mm, along with imaging findings of alveolar bone resorption exceeding 1/2 of the root length. ? Excluding attachment loss caused by non-periodontal causes; ? Voluntarily participated in this clinical study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: ? Suffering from systemic diseases that can affect the progression of periodontal disease, such as diabetes, hypertension, hyperlipidemia, uremia, etc; ? Received orthodontic treatment within the last 6 months; ? Periodontal treatment other than supragingival cleaning within the last 6 months; ? Taking antibiotics within the last 3 months; ? Suffering from oral diseases other than periodontitis, such as active caries, mucosal disease, apical periodontitis, pericoronitis, and oral cancer; ? Being pregnant or postpartum or breastfeeding.

Design outcomes

Primary

MeasureTime frame
probing depth;clinical attachment loss;bleeding of probe;

Countries

China

Contacts

Public ContactJunlin He

Shanghai Stomatological Hospital

hjlls2009@163.com+86 21 6360 1025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026