Amblyopia
Conditions
Interventions
normal control group:none
Monocular masking treatment group:Perform monocular occlusion therapy for 2h per day, at least 5 days per week, for 12 weeks of maintenance therapy
Binocular vision treatment group :Home training of amblyopic patients in binocular vision therapy using the Amblyopia Binocular Vision Therapy System for 1.5 hours per day, at least five days per week
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: Normal control group: 1) 6-18 years old, subject to his/her written consent, and gender-neutral; 2) Best-corrected visual acuity = 1.0 in both eyes; difference in visual acuity between eyes = 2 lines. Experimental group: 1) 6-18 years old, subject to their written consent, gender is not limited; (2) Monocular refractive amblyopia: best-corrected visual acuity =0.6 in the amblyopic eye, visual acuity =0.8 in the contralateral eye; visual acuity difference =2 lines between eyes. Visual acuity difference between two eyes = 2 lines; (3) Have normal thinking and language communication ability, and can actively cooperate with the treatment as required; (4) Parents agree to be randomized and sign an informed consent form. A personally signed and dated informed consent form A personally signed and dated informed consent form indicates that the patient (or legal representative) has been informed of all relevant information about the study.
Exclusion criteria
Exclusion criteria: 1) Presence of organic lesions that cause reduced visual acuity; 2) Paracentric gaze; 3) Systemic diseases affecting intelligence, etc; 4) Other conditions that, in the judgment of the investigator, make participation in the study unsuitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the degree and extent of neural activity in area V1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in vision and visual function; | — |
Countries
China
Contacts
Public ContactHong Liu
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed