Colorectal cancer liver metastases
Conditions
Interventions
Radical surgical resection group for colorectal cancer liver metastasis:NA
Sponsors
Beijing Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Patients with colorectal cancer liver metastases (CRLM) confirmed histologically to have undergone radical resection (including surgical resection followed by combined radiofrequency ablation to achieve radicality). 1) For patients with CRLM in whom the primary tumor was resected first and only liver metastases are currently present: a. Liver metastases are resected to achieve radicalization; b. Liver metastases are resected intraoperatively combined with postoperative ablation to achieve radicalization; 2) For patients with CRLM who currently have both primary tumor and liver metastases: a. Simultaneous resection of the primary tumor and liver metastases (or combined postoperative radiofrequency ablation) to achieve radicalization; b. Resection of the liver metastases (or combined postoperative radiofrequency ablation) in the first stage, and resection of the primary tumor in the second stage to achieve radicalization. 2. Male or female aged over 18 years and under 80 years; 3. Eastern Cooperative Oncology Group (ECOG) score as 0-2; 4. The subjects must sign the informed consent, indicating that they understand the purpose of the study, understand the necessary procedures of the study, and are willing to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe medical comorbidities or major organ insufficiency; 2. Patients with symptoms of severe bleeding, perforation, and intestinal obstruction; 3. Colorectal cancer patients presenting with metastases to distal organs other than the liver; 4. Patients treated with radiofrequency ablation alone; 5. Nonradical surgical resection; 6. A history of other tumors; 7. Other conditions in which the investigator believes that the patient should not participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease-free survival; | — |
Countries
China
Contacts
Public ContactKun Wang
Beijing Cancer Hospital
Outcome results
None listed