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Clinical observation of methadone in the treatment of refractory cancer pain by the ad libitum method

Clinical observation of methadone in the treatment of refractory cancer pain by the ad libitum method

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077867
Enrollment
Unknown
Registered
2023-11-22
Start date
2022-11-10
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer pain

Interventions

Case series:None

Sponsors

Eastern Theater General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
21 Years to 71 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-80 years old, gender unlimited (2) cancer pain patients who use large doses of opioids, that is, the 24-hour dose = 200mg morphine equivalent dose (MED) (3) NRS = 4 points

Exclusion criteria

Exclusion criteria: (1) Methadone allergy (2) patients with swallowing dysfunction (3) ECG QTc > 450ms (4) patients with severe cardiopulmonary dysfunction or liver and kidney failure (5) patients with tumor brain metastasis (6) pregnant and lactating women (7) patients refused to participate in this trial (8) patients with mental disorders could not cooperate with physical examination and related evaluation

Design outcomes

Primary

MeasureTime frame
Pain score;

Secondary

MeasureTime frame
Record the number of remedies;quality of life;satisfaction;

Countries

China

Contacts

Public ContactJin Yi

Eastern Theater Command General Hospital

kimye@vip.163.com+86 138 5151 6946

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026