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Clinical observation of withdrawal reactions when systemic opioids are converted to intrathecal morphine analgesia

Clinical observation of withdrawal reactions when systemic opioids are converted to intrathecal morphine analgesia - Clinical observation of withdrawal reactions when systemic opioids are converted to intrathecal morphine analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077866
Enrollment
Unknown
Registered
2023-11-22
Start date
2022-11-10
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory cancer pain

Interventions

Case series:None

Sponsors

Department of Pain, Eastern Theater General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Patients with opioid tolerance (oral morphine equivalent=60mg/d, duration =1 week) and meeting the diagnostic criteria for refractory cancer pain; (2) Subjects or authorized family members sign informed consent for surgery and treatment.

Exclusion criteria

Exclusion criteria: (1) Morphine allergy; (2) intrathecal drug infusion port implantation is contraindicated; (3) Those who cannot tolerate surgery due to failure or disorder of important organs; (4) Consciousness disorder or mental abnormality, unable to cooperate with pain, withdrawal response assessment or unable to self-control analgesia; (5) Pregnant and lactating women; (6) Patients who have participated in other clinical trials in the past 3 months;

Design outcomes

Primary

MeasureTime frame
The incidence and influencing factors of withdrawal reactions;

Secondary

MeasureTime frame
Duration of withdrawal and degree of withdrawal;

Countries

China

Contacts

Public ContactYi Jin

Eastern Theater General Hospital

kimye@vip.163.com+86 138 5151 6949

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026