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Comparisons of the clinical outcomes of Centurion® active fluid system with a low IOP setting and gravity fluid system with a normal IOP setting for cataract patients with low corneal endothelial cell density

Comparisons of the clinical outcomes of Centurion® active fluid system with a low IOP setting and gravity fluid system with a normal IOP setting for cataract patients with low corneal endothelial cell density

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077865
Enrollment
Unknown
Registered
2023-11-22
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Interventions

Active fluid system group:Using Alcon Centurion platform with the active fluid mode+ Low intraocular pressure setting (30mmHg)
Gravity fluid system group:Using Alcon Centurion platform and gravity fluid mode+ Traditional intraocular pressure setting (80cmH2O)

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: - age related cataract patients aged between 60-85 years old - 500 count/mm2 <Corneal endothelial cells count<1500(count/mm2) - moderate age-related cataract, nuclear sclerotic grade II and III (Lens Opacities Classification System, version III, LOCS III ) - Intended to be implanted with AcrySof IOLs

Exclusion criteria

Exclusion criteria: - History of eye surgery within 1 month - Corneal edema - Preoperative shallow anterior chamber (ACD<2.0mm) - Intraoperative dilated pupil size <6mm - Preexisting ocular pathology, such as macular disease, RD,uveitis, glaucoma, iridodialysis, central corneal opacity, and ocular implantations such as implantable collamer lens (ICL) or silicon oil - Systemic connective tissue disease, Rheumatism, rheumatoid - Unable or unwilling to attend follow-up visits

Design outcomes

Primary

MeasureTime frame
Central Corneal Rhichness;

Secondary

MeasureTime frame
Corneal endothelial cell density;

Countries

China

Contacts

Public ContactJing Hong

Peking University Third Hospital

hongjing196401@163.com+86 10 8226 6455

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026