duodenal papilla lesions (low-grade dysplasia/high-grade dysplasia/canceration)
Conditions
Interventions
Routine BIOPSY group:NA
Sponsors
Department of Gastroenterology, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) aged between 18 and 75 years old 2) Confirmed FAP (CFAP or AFAP) A. CFAP (meets all of the following criteria) ? Patients with colorectal adenomatous polyps > 100 with an earlier age of onset (polyps usually develop between 10 and 20 years of age and gastrointestinal symptoms develop after 20 years of age) ? accompanied by extraintestinal manifestations such as CHRPE, osteoma, and desmoid tumors ? Autosomal dominant inheritance B. AFAP (meeting any of the criteria, excluding family members with >100 colorectal adenomas at the age 30 years old and had 10 to 99 colorectal adenomas ? There is one patient in the family with age of onset > 30 years old and had 10-99 adenomas, and a first-degree relative had a history of colorectal cancer with adenoma 3) perform upper gastrointestinal endoscopy in our hospital 4) those who signed the informed consent form
Exclusion criteria
Exclusion criteria: 1) patients who had undergone pancreaticoduodenectomy 2) patients with serious heart, liver, kidney or lung diseases 3) patients with inadequate gastrointestinal preparation and difficulty in clearly observing the mucosa
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hazard ratio;95% confidence interval; | — |
Countries
China
Contacts
Public ContactZhu Wang
Department of Gastroenterology, West China Hospita
Outcome results
None listed