Overactive Bladder Syndrome
Conditions
Interventions
OAB group (functional MRI before and after medication):None
control group (functional MRI):None
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for patients 1. Clinical Diagnosis of OAB: urgency, with or without urine frequency and noctuira 2. Age 18 years old or more 3. Cooperate with MRI examination and questionaire 4. Planning for oral medication and follow-up 5. Willing to sign the informed consent Inclusion criteria for volunteer 1. Age 18 years old or more 2. Cooperate with MRI examination and questionaire 3. Willing to sign the informed consent
Exclusion criteria
Exclusion criteria: 1. With Urinary tract infection and/or abnormal urine test (white blood cell =100/ul) 2. Residual urine =100ml 3. Other diseases with urine urgency such as incontinence 4. Central nervous system disease within the past 6 months, including brain trauma, brain hemorrhage, brain infarction, intracranial tumor, intracranial infection, brain surgery, abuse of psychoactive drugs, etc. 5. Transurethral surgery within 6 months 6. With claustrophobia 7. With fixed metal dentures 8. With heart pacemaker, coronary vessel stent, metal internal fixation, etc., unsuitable for fMRI 9. Combined with urinary stones, urinary tumor or urinary inflammatory lesions. 10. Other conditions deemed unsuitable for fMRI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fMRI-BOLD analysis;SAS anxiety score; | — |
Secondary
| Measure | Time frame |
|---|---|
| OAB syndrome score (OABSS);MOCA score;CES-D score; | — |
Countries
China
Contacts
Public ContactDaoying Geng, Jie Zheng
Department of Urology, Huashan Hospital affiliated to Fudan University Department of Radiology, Huashan Hospital affiliated to Fudan University
Outcome results
None listed